This may help explain why GLP-1s have been particularly effective for patients with binge eating, compulsive snacking, or post-diet rebound eatingbehaviors rooted in neurological and emotional loops, not just willpower
Without adequate ATP, neurons cannot maintain their resting membrane potentials, fire action potentials efficiently, or synthesize the neurotransmitters required for memory, focus, and emotional regulation
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Molecular regulation of fatty acid -oxidation extends beyond core enzymatic machinery (CPT1, CPT2) to include sophisticated transcriptional and post-translational control mechanisms involving AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor (PPAR), and peroxisome proliferator-activated receptor coactivator-1 (PGC1) (4244)
